Connects Claude to the GTEx (Genotype-Tissue Expression) project's human gene expression data via Pipeworx's gateway. You get five tools: look up gene metadata by Gencode ID or symbol, pull median expression levels across tissues in TPM, find top expressed genes for a specific tissue, query significant single-tissue eQTLs, and list available tissues. Useful when you're doing genomics research or building tools that need to cross-reference gene symbols with expression patterns in specific human tissues. Part of Pipeworx's broader gateway covering 250+ data sources, but available as a standalone endpoint if you only need GTEx.
GTEx MCP.
Part of Pipeworx — an MCP gateway connecting AI agents to 673+ live data sources.
| Tool | Description |
|---|---|
gene | Gene metadata by Gencode id or symbol. |
median_expression | Median expression across tissues for a gene (TPM). |
top_expressed_genes | Top expressed genes for a tissue. |
single_tissue_eqtls | Significant single-tissue eQTLs for a gene. |
tissues | List of tissues. |
Add to your MCP client (Claude Desktop, Cursor, Windsurf, etc.):
{
"mcpServers": {
"gtex": {
"url": "https://gateway.pipeworx.io/gtex/mcp"
}
}
}
Or connect to the full Pipeworx gateway for access to all 673+ data sources:
{
"mcpServers": {
"pipeworx": {
"url": "https://gateway.pipeworx.io/mcp"
}
}
}
Instead of calling tools directly, you can ask questions in plain English:
ask_pipeworx({ question: "your question about Gtex data" })
The gateway picks the right tool and fills the arguments automatically.
MIT